QUACKERY

Home | HERBAL REMEDIES--NCAHF warning | CHIROPRACTICS: 19th CENTURY QUACKERY | CHIROPRATICS EVALUATED | CHIROPRATICS: a medical organization's position paper | CHIROPRACTORS AND IMMUNIZATION | HOMEOPATHY: ITS HISTORY, ITS ABSURDITY | MESSAGE THERAPY | CHELATION THERAPY | HERBAL HUCKSTERING ON TV, AVLIMIL STUDY | Organic, Natural Compounds compared to synthetic ones, a Summary--jk | HGH, a widely used hormone for increasing muscle mass | Alternative Treatments Immune Response to Cancer | MEDICINE AND THE PSYCHOLOGY OF BELIEF | WEIGHT LOSS PROMOTIONS | HOW TO EVALUATE MEDICAL DISCOVERIES | BAD DATA FROM DRUG COMPANIES--Scientific American | Problems with FDA Oversight--Consumer Report | AMALGAM FILLINGS--absolutely safe | High Fiber Diet & Skepticism | FAD ANTIAGING EXPOSED | Migraines, research, and Questionable Treatments | Hydrazine Sulfate, not an anti-cancer agent | Electromagnetic Fields not a hazard | MAGNETIC & ELECTROMAGNETIC THERAPY | Ginko, Fails the Test | LINKS
MAGNETIC & ELECTROMAGNETIC THERAPY

ANOTHER CASE OF HARM DONE BY A
 
PRESS WITHOUT THE GUIDANCE OF
 
SOUND SCIENCE.  FUNDS, TIME, AND
 
THE FAILURE TO CHOOSE THE BEST
 
AVAILABLE TREATMENTARE THE
 
RESULTS OF THE MISINFORMED
 
CHOICES MADE.  WHAT FOLLOWS
 
SHOWS ANOTHER POPULAR COUNTRA
 
TO MEDICIAL SCIENCE TREATMENT TO
 
BE WITHOUT MERIT.

Magnetic and Electromagnetic Therapy

By David W. Ramey, DVM


One of the more popular therapies for the treatment of a variety of conditions in human and veterinary medicine is the application of a magnetic field. The biological effects of low-level magnetic fields have been studied since the 1500s. The crucial question, however, is whether these effects have any physiological significance. Many claims have been made for the therapeutic effectiveness of magnetic fields, but are there any good reasons for believing them?

History

The idea that magnetic therapy could be used to treat disease began in the early 16th century with the Swiss physician, philosopher, and alchemist Paracelsus, who used magnets to treat epilepsy, diarrhea, and hemorrhage.1 Magnetic therapy became more popular in the mid-18th century when Franz Mesmer, an Austrian doctor who also helped begin the fields of hypnotism and psychoanalysis (and from whose name the word "mesmerize" was coined), opened a popular magnetic healing salon in Paris. The purpose of the salon was to treat the untoward effects of the body's innate "animal magnetism." In spite of continued condemnation by the scientific community, magnetic therapy became a popular form of treatment by the lay community.

Over the next few centuries, magnetic therapy developed into a form of quackery. In 1799, Elisha Perkins, a Connecticut physician and sometime mule trader, advocated the use of "metallic tractors" for the treatment of various diseases of humans and horses.2 The user of the tractors (small metal magnetic wedges) swept the tractors over the injured area for a few minutes to "draw off the noxious electrical fluid that lay at the foot of suffering." Subjects and observers perceived immediate benefits. They reported their testimonials and Perkins became very rich. Magnetic tractors failed to prevent Dr. Perkins' death due to yellow fever in 1799.

In the late 1800s, the Sears catalogue advertised magnetic boot inserts. Magnetic caps and clothing (with over 700 magnets) were available by mail order from Thatcher's Chicago Magnetic Company. 3 Dr. Thatcher asserted that "magnetism properly applied will cure every curable disease no matter what the cause."4 At the turn of the 20th century, Dr. Albert Abrams, named the "Dean of 20th Century charlatans" by the American Medical Association, postulated that each organ system and patient was "tuned" to a characteristic electromagnetic wavelength. By the time of World War II, physiologic effects of electromagnetic fields no longer received much attention in medical journals.

The history of quackery in the use of magnets has obscured scientific investigations performed on the medical effects of magnetic and electromagnetic fields. From a biophysics standpoint, a distinction is made between the two therapies; magnetic and electromagnetic are not the same.

Electricity and Magnetism

Electromagnetism was first discovered in the 1800s by the English physicist Michael Faraday, who determined that a magnetic field could be generated by running an electric current through a wire coil. Conversely, a changing magnetic field can generate an electric voltage; the magnetic field must change to have any electrical effect (hence, the term pulsating electromagnetic field therapy, which generates rising and falling levels of a magnetic field.)

The biological effects of pulsating electromagnetic fields are hypothesized to be due to electrical rather than magnetic forces. Magnetism generates a voltage in tissue according to the equation:

V = n x a x dB/dt

V = Voltage

n = number of turns in the electromagnetic coil

a = area of the loop

dB/dt = The rate of change of magnetic field with respect to time, with B representing the strength of the magnetic field (in Teslas). For example, if B goes from zero to 1 Tesla in 1 millisecond, then dB/dt = 1000 Teslas/sec.

Based on this equation, a static magnetic field cannot generate an electrical voltage, as the dB/dt component of the equation, is zero, as is the voltage induced by the field. Thus, any effects of a static magnetic field on tissue cannot be electrical in nature.

Pulsating Electromagnetic Field Therapy

Extracellular matrix synthesis and repair are subject to regulation both by chemical agents (such as cytokines and growth factors) and physical agents, principally mechanical and electrical stimuli. The precise nature of such electromechanical signals is not known, however. In bone, mechanical and electrical signals may regulate the synthesis of extracellular matrix by stimulating signaling pathways at the cell membrane.6,7 In soft tissue, alternating current electrical fields induce a redistribution of integral cell membrane proteins which, hypothetically, could initiate signal transduction cascades and cause a reorganization of cytoskeletal structures. 8 However, the hypothesis that electrical signals may be responsible for information transfer in or to cells has neither been proved nor disproved.

There is ample evidence that electrical activity exists in the body at all times. For example, electrical currents can be measured in the beating heart and are also generated in the production of bone. Endogenous electrical current densities produced by mechanical loading of bone under physiologic conditions approximate 1 Hz and 0.1 - 1.0 microA/cm2 .9 Thus, it is theorized that application of an appropriate electrical current, either directly through wires or indirectly through induction by a magnetic field, may affect tissues in several ways. The word appropriate in the preceding sentence is important since cells and tissues respond to a variety of electrical signal configurations in ways that suggest a degree of specificity for both the tissue affected and the signal itself.

The most widely studied application of electromagnetic field therapy in human medicine is in fracture therapy. Although the mechanisms remain undetermined, several studies report that electrical fields generated by pulsating electromagnetic field therapy stimulate biologic processes pertinent to osteogenesis10,11,12 and bone graft incorporation. 13,14 This form of therapy is approved for the treatment of delayed and non-union fractures in humans in the U.S. by the United States Food and Drug Administration. Effectiveness of the treatment is supported by at least two double-blind studies.15,16 Pulsating electromagnetic field therapy, however, delays the healing of fresh experimentally induced fractures in rabbits.17

Pulsating electromagnetic field therapy has also been evaluated in the treatment of soft tissue injuries, with the results of some studies providing evidence that this form of therapy may be of value in promoting healing of chronic wounds (such as bedsores)18 , in neuronal regeneration,19,20 and in many other soft tissue injuries.21,22 results of a recent study in an experimental Achilles tendinitis model in rats indicated that there was an initial decrease in water content in injured tendons treated with pulsating electromagnetic field therapy but that all treated groups were equal to controls by 14 days.23The limited value of this form of therapy in the treatment of tendon injuries may be due in part to the lack of significant electrical activity in tendons, activity that could be altered by a pulsating electromagnetic field.

In contrast, a number of investigators have been unable to show any effect of low-level electromagnetic fields on tissue healing. One study, for example, failed to identify any beneficial effect of applying a magnetic field to a non-healing fracture24 and concluded that the long periods of immobilization and inactivity required for the application of the magnetic field therapy were just as likely to be responsible for tissue healing.

Criticisms of pulsating electromagnetic field studies include: some of the studies are poorly designed; independent trials have not been conducted to confirm positive results; and the electrical fields induced by the machines are several orders of magnitude lower than are required to alter the naturally occurring electrical fields that exist across biological membranes.25 Even proponents of the therapy concede that much work needs to be done to optimize such variables as signal configuration and duration of treatment before pulsating electromagnetic field therapy can be generally recommended.26

Static Magnetic Field Therapy

Magnetic devices that radiate an unchanging magnetic field are available in a variety of configurations such as pads, bandages, and even magnetic mattresses. Scientific studies do not support claims of efficacy. Furthermore, a mechanism of action by which such devices might exert these effects remains elusive. Because static magnetic fields do not change, there can be no electrical effect. Hypotheses for an effect of a static field include influencing the electronic spin rate states of chemical reaction intermediates27,28 and influencing cyclical changes in the physical state(s) of water.29 Importantly, neither of these proposed effects has been demonstrated in biological systems under physiological condition.30

In spite of a lack of demonstrable mechanism of action, proponents of applying static magnetic field therapy to injured or painful tissues generally attribute their alleged effects to an increase in local blood circulation. Unfortunately, the scientific evidence in supporting this hypothesis is tenuous at best.

Blood, like all tissues, contains electrically charged ions. A physics principle known as Faraday's Law states that a magnetic field will exert a force on a moving ionic current. Furthermore, an extension of Faraday's law called the Hall effect states that when a magnetic field is placed perpendicular to the direction of flow of an electric current, it will tend to deflect and separate the charged ions. While the deflection of ions will be in opposite directions depending on the magnetic pole encountered and the charge of the ion, this force is not based on the attraction or repulsion of like and unlike charges.

The Hall effect implies that when a magnet is placed over flowing blood in which ionic charges (such as Na+ and Cl-) exist, some force will be exerted on the ions. Furthermore, the separation of ionic charges will produce an electromotive force, which is a voltage between points in a circuit. In theory, this produces a very small amount of heat. These physical effects, which do exist, provide the basis for a quasi-scientific theory to account for the purported effects of static magnetic field therapy. For example:

When a magnetic field with a series of alternating North and South poles is placed over a blood vessel, the influence of the field will cause positive and negative ions (for example, Na+ and Cl-) to bounce back and forth between the sides of the vessel, creating flow currents in the moving blood not unlike those in a river. The combination of the electromotive force, altered ionic pattern, and the currents causes blood vessel dilation with a corresponding increase in blood flow. 31

The problem with using Faraday's law and the Hall effect to explain the purported effects of static magnetic pads is that the magnitude of that force applied by the field is infinitesimally small. Two facts account for the lack of effect. First, the magnetic field applied to the tissue is extremely weak. Second, the flow of the ionic current (i.e., the blood) is extremely slow, especially when compared to the flow of electric current. However, it is possible to estimate the forces applied to flowing blood by a weak magnetic field as long as the strength of the magnetic field applied, the velocity of the flowing blood, and the number of the ions in the blood are known.

Magnetic field strength is measured in one of two units: 1 Tesla = 104 Gauss. The magnetic field strength of a Norfield's MAGNETIChockwrapTM(for horses) measured at California Institute of Technology had a field strength of 270 Gauss at the level of the pad and 1 Gauss at a distance of 1 cm from the pad. Tissues purportedly affected by the pads lie at least 1 cm away from them; 1 Gauss is approximately the magnetic field strength of the earth.32 Promotional information for Bioflex pads asserts an "independent laboratory" has measured the field strength of their pads at 350 Gauss and that "optimum" field strength for the purported healing effects is less than 500 Gauss.33 Regardless, these are very weak magnetic fields.

Considering the applied magnetic field at 250 Gauss (0.025 Tesla) and the velocity of blood flow v as 1 cm/sec (0.01 m/sec), the electric field to which an ion in the blood is exposed can be calculated as:

E = v x B = 2.5 x 10-4 Volts/meter/sec

Hence, the change in electric potential (a psuedo-Hall effect) across a 1 mm diameter blood vessel can be estimated at a minuscule 2.5 x 10-7 Volts.

Ions of opposing charges will move in opposite directions when moving through a static magnetic field. The separation of charges, known as the drift velocity, can also be calculated. In the case of Na+ and Cl- ions in flowing blood under the influence of a 250 Gauss magnetic field, the increased separation of the positive sodium and the negative chloride ions will be about 0.2 Angstroms per second, or about 1/10 the diameter of an atom. This can be compared with the random drift distance in one second that results from the thermal agitation imparted by the heat of the horse's body of about 0.25 mm/sec. Stated in another fashion, the ions will travel farther from thermal agitation than from the 250 Gauss magneto-electrical field drift by a factor of about 10 million.34

Any magnetic forces generated by a static field affecting fluid movement in blood vessels would have to overcome both the normal, pressure-driven turbulent flow of blood propelled by the heart and the normal thermal-induced Brownian movement of the particles suspended in the blood. Given the strong physical forces that already exist in a blood vessel, any physical forces generated by a static magnetic field on flowing blood, particularly those as weak as those associated with therapeutic magnetic pads, are extremely unlikely to have a biological effect.

Magnetic Pad Design

At least one manufacturer of magnetic pads (Magnaflex/BioflexTM) asserts that the effect of charge separation can be increased by alternating north and south magnetic poles. Alternating magnetic poles are most commonly seen in refrigerator magnets. By alternating the magnetic poles, an increased magnetic gradient is created, which increases the ability of the magnets to stick to the refrigerator. Paradoxically, alternating poles decrease the magnetic field strength of the magnet because the fields tend to cancel each other out as they extend from the magnet. Thus, while alternating poles would exert opposite forces on ions flowing through the magnetic field, the decrease in magnetic field strength would lessen any potential influence of the magnetic field on the target ions. Nor does there appear to be any consensus in the industry as to the ideal design for the pads. In fact, a competing manufacturer asserts that, "Leading scientists agree that unipolar magnets are superior to bi-polar,"35 although neither the scientists nor the supporting research are identified.

Further proprietary design information regarding at least one commercial source of magnetic pads (BioflexTM pads) would also appear to be irrelevant regarding biologic effects. Promotional information for the pads indicates that the "concentric circle" arrangement of the pads increases the likelihood that the magnetic field would be applied perpendicular to flowing blood, thereby maximizing the Hall effects. In fact, because blood vessels run randomly throughout the three dimensions of any tissue, there can be no "preferred" arrangement of the magnetic field that would favor its perpendicular orientation to the flow of blood.

Studies on Static Magnetic Fields and Blood Flow

A number of studies have investigated the effects of static magnetic fields on blood flow. Studies commissioned by the makers of one type of magnetic pad showed that exposure of a highly concentrated saline solution in a glass capillary tube increased the flow of the solution. This study has been often cited by manufacturers of static magnetic devices as evidence that magnetic field therapy can potentially affect the circulation of blood. Although the mechanism for the increase in saline flow is not apparent, it certainly could not have been related to any dilatory effect on the walls of the glass capillary tube. The investigator who performed the study concluded that the results of the experiments performed using highly concentrated saline in a glass tube should not be extrapolated to effects that would be expected with flowing blood.36

A second study evaluated the effects of the pads in the distal limbs of horses using nuclear scintigraphy, a technique that is useful in identifying areas of blood vessel dilation and inflammation. That study concluded that, "Scintigraphy was performed in the vascular, soft tissue, and bone phase using a cross over trial to demonstrate increased blood flow and metabolic activity as a result of the local application of a permanent magnetic pad on the equine metacarpus. A highly significant increase was evident in the three phases."37 The results of this study have been used repeatedly to suggest that magnetic pads promote blood circulation to the areas under the pads.

This study, which is apparently the only one to state that a static magnetic field affects blood circulation, is open to criticism. The experimental model, which compared the results of scans on one "treated" limb vs. the non-treated limb is inherently inaccurate, as one forelimb cannot be used as a control for the other in scintigraphic studies (each limb should be used as its own control). Furthermore, the design of the study was flawed, as a bandage and magnetic pad were applied to one limb while a bandage only was applied to the other. A more appropriate control would have been a bandage and a demagnetized pad. The radioisotope chosen for the study was not appropriate to determine blood circulation accurately. Finally, the study measured absolute scintigraphic counts, when the use of relative perfusion ratios would have been more appropriate.38

Numerous other studies have failed to show any effect of magnetic fields on blood circulation. For instance, no effect of dental magnets on the circulation of blood in the cheek could be demonstrated.39 Scintigraphic evaluation of blood flow in mice exposed to two strengths of pulsating electromagnetic field force failed to demonstrate any circulatory effects.40 A study on the circulatory effects of a magnetic foil was unable to show any effect in the skin of human forearms41 and application of a magnetic foil to healing wounds in rats showed no significant effects.42 A study in horses showed that application of a magnetic pad over the tendon region for 24 hours showed no evidence of temperature increase in treated limbs vs. placebo controlled limbs, using thermographic measurements as an indirect assessment of blood circulation to the area.43

As a more practical matter, if a magnet caused local increases in circulation, one would expect the area under the magnet to feel warm or become red as a result. Such an effect is not reported when magnets are held in the hand. Furthermore, one would expect any circulatory effects produced by very weak magnetic fields to be magnified in stronger magnetic fields. However, no circulatory effects have ever been reported in magnetic resonance imaging machines, in which the magnetic forces generated are two to four orders of magnitude greater than those produced by therapeutic magnetic pads. In studies of humans exposed to magnetic fields up to 1 Tesla (10,000 Gauss) there was no evidence of alterations in local blood flow at the skin of the thumb or at the forearm.44 Even a 10 Tesla magnetic field is predicted to change the vascular pressure in a model of human vasculature by less than 0.2%, and experimental results of the effects of strong magnetic fields on concentrated saline solutions are in general agreement with these predictions.45

Based on the available scientific data, one must conclude that if there is an effect of static magnetic fields on blood circulation, there is no known biological mechanism by which that effect is generated. One may also postulate that the boots, blankets, and bandages in which the magnets are sewn have some sort of a thermal effect that is independent of the magnetic field (and could be duplicated with any form of bandaging).

Magnetic Fields and Pain Relief

Both static and pulsating electromagnetic field therapy have also been promoted as being beneficial for the relief of pain. As with other proposed effects, there is no known mechanism of action by which application of a magnetic field produces biological effects. If they are effective in the relief of pain, it is unlikely that the effect is related to a reduction in nerve conductivity; the field required to produce a 10% reduction in nerve conductivity is roughly 24 Tesla.46

Studies evaluating the effects of pulsating electromagnetic fields in the relief of pain have shown conflicting results. Pulsating electromagnetic field therapy has reportedly provided pain relief in the treatment of osteoarthritis of the human knee and cervical spine,47,48 in the treatment of persistent neck pain,49 and in the treatment of women with chronic refractory pelvic pain.50 However, electromagnetic therapy showed no benefit in the relief of pain due to shoulder arthritis51, and a 1994 summary of published trials of non-medicinal and noninvasive therapies for hip and knee osteoarthritis concluded that there were insufficient data available to draw any conclusions on the efficacy of the therapy.52 Paradoxically, another study in humans showed that magnetic treatment actually induced hyperalgesia in a tooth pain model.53

Pads that apply a static magnetic field are also promoted as having pain-relieving effects. Poorly controlled studies from the Japanese literature suggest that static magnetic devices were highly effective in alleviating subjective symptoms such as neck, shoulder, and other muscular pain.54,55 One controlled, double-blind pilot study suggested that magnetic pads were effective in the relief of myofascial or arthritic-like pain in postpolio syndrome,56 although every patient in the study, whether being treated with a placebo or a magnet, showed relief from pain. However, other studies have concluded that a magnetic foil offered no advantage over plain insoles in the treatment of pain of the human heel57 and that a magnetic necklace had no effect on neck and shoulder pain.58 It has also been suggested that there is a strong placebo effect at work in the perception of pain relief offered by static Magnetic devices.59

Clinical Use of Magnetic Fields in Veterinary Medicine

Magnetic and electromagnetic devices appear not to be used on small animals. However, the devices are widely advertised in magazines targeted at horse owners. Pulsating electromagnetic field therapy is typically applied to horses with boots or blankets. Some of the variables of the magnetic field generated (such as the amplitude and frequency of the signal) can be controlled using this form of magnetic therapy. However, changes in these variables appear to affect different tissues in different ways, and those ways are not well defined, making selection of ideal field strength of the therapy problematic.

The other way to apply a magnetic field to a horse is by attaching a magnetic pad. This form of therapy generates a continuous, static magnetic influence on the targeted tissue; however, the magnetic field cannot be modulated. The principle advantage of this form of magnetic therapy is that it is relatively inexpensive (compared to the cost of the machines) and easy to apply; the disadvantage is that as yet there is no scientific evidence of an effect.

The absence of a plausible scientific theory for a mechanism of action should never override reliable strong clinical evidence of an effect. For example, the mechanism of aspirin was not known for many years, although the drug was clinically effective. However, there appear to be no published scientific studies available that demonstrate that any form of magnetic field therapy is valuable in the treatment of disease conditions of the horse.

Daily electromagnetic therapy did increase the concentration of blood vessels in surgically created defects of equine superficial digital flexor tendon, but the maturation of the repair tissue and the transformation of collagen type (two essential components in the healing process of tendon) actually were delayed by the treatment in tendon samples collected at 8 to 12 weeks after surgery.60 No benefit could be demonstrated in the healing of freshly created bone injuries treated with pulsating electromagnetic field therapy when compared to untreated control limbs, 61 although another study did suggest an increase in bone activity under pulsating electromagnetic field treatment when holes were drilled in horse cannon bones.62 Topical treatment with a pulsed electromagnetic field showed little effect on metabolism of normal horse bone in another study.63 Unfortunately, the principle application of pulsating electromagnetic field therapy in people, for delayed and non-union fractures, is of little apparent use in horses.

Magnetic Therapy and Pseudoscience

In spite of hundreds of years of investigation, there still appears to be no place for magnetic therapy in scientific medicine. While legitimate investigations are taking place, many aspects of magnetic therapy carry hallmarks of pseudoscience. For example:

  • Vague, unsupported claims of effectiveness. One device advertises that "leading scientists agree that unipolar magnets are superior to bipolar." The "leading scientists" are not identified. The company also claims to have "tens of thousands of very satisfied users."
  • Misuse of defined scientific terminology. The discovery of a "unipolar" magnet (see above) or magnetic monopole would lead its discoverer to an almost immediate Nobel prize, as magnetic monopoles have not been shown to exist. One company advertises its "Tectonic" magnets (tectonics is a geologic term referring to the study of the earth's structural features.)
  • Mischaracterization of medicine. One company warns about the side effects of taking "too many pills" and states that, "Using magnets means you are not putting anything into your stomach that might cause upset or damage." Another company describes their magnets as "natural as nature" and "wholistic" [sic]. While magnets may not have any side effects, they may not have any effects, either.
  • Inaccurate claims. One company states that studies at various universities have "proven" that static magnets increase blood flow. This appears to be contrary to fact.
  • Predicted phenomena remain slippery. As experimental and theoretical work progresses, more and more sound evidence for the related phenomena should appear.64 So far, such evidence remains elusive in the field of magnetic therapy.
  • No deepening evidence. In spite of hundreds of years of experience and investigation, the "state of the art" in magnetic therapy appears to have increased little since the days of Franz Mesmer.

Summary

Whenever an injury to tissue occurs, the goal of any medical therapy is to help allow healing of that injury so that, to the extent that it can be done, the injured tissue is returned to full normal function as quickly as possible. The quality of tissue repair and the speed with which that repair can be accomplished are the two major variables in the healing of any injury. Any medical therapy that could be demonstrated to affect either variable (or better yet, both of them) would be extremely valuable to the medical field.

However, assessing whether or not a particular medical therapy is effective in those regards is somewhat problematic. The old adage, "Time heals all wounds," is largely true. Many diseases are self-limiting and the body is able to heal itself with no intervention whatsoever. For example, according to one source, approximately 70 per cent of all acute infectious disease conditions of the horse are adequately dealt with by the host's defenses.65 That suggests that whichever method of treatment is selected, 7 out of 10 times, the problem will get better. If healing occurs while a device touted to promote healing is applied to an injured or infected area, that device often receives the credit.

Explanations that magnetic fields "increase circulation," "reduce inflammation," or "speed recovery from injuries" are simplistic and are not supported by the weight of experimental evidence. The effects of magnetic fields on body tissues are complex and appear to vary from tissue to tissue and from different intensities and duration of the magnetic field applied. The nature of the magnetic devices make them amenable to randomized, controlled, double-blind studies that are, for the most part, lacking. Although the therapies appear to be harmless, that does not also mean that they are useful.

References

  1. Mourino, M. From Thales to Lauterbur, or from the lodestone to MR imaging: magnetism and medicine. Radiology 180: 593-612, 1991.
  2. Herholdt and Rafn, Experiments with the Metallic Tractors in Rheumatic and Gouty Affections, Inflammations and Various Tropical Diseases, Royal Academy of Sciences, Copenhagen, Denmark, 1799.
  3. Macklis, R. Magnetic Healing, Quackery and the Debate about the Health Effects of Electromagnetic Fields. Annals of Medicine 118(5): 376-383, 1993.
  4. Thatcher, C. Plain road to health without the use of medicine. Jameson and Morse, Chicago, IL, 1886.
  5. Milstead, K, David, J and Dobelle, M. Quackery in the medical device field. Proceedings of the Second National AMA/FDA Congress on Medical Quackery. Washington, D.C., Oct. 25-26, 1963.
  6. Davidovitch, Z., et al. Biochemical mediators of the effects of mechanical forces in electric currents on mineralized tissue. Calcif Tissue Int 36: s86-s79, 1984.
  7. Aaron, R. and Ciombor, D. Acceleration of Experimental Endochondral Ossification by Biophysical Stimulation of the Progenitor Cell Pool. J Orthop Res 14(4): 582-89, 1996.
  8. Cho, M., et al. Reorganization of microfilament structure induced by ac electric fields. FASEB J 10: 1552-1558, 1996.
  9. MacGinitie, L.A., Gluzbank, Y.A. and Grodzinski, A.J. Electric Field Stimulation can Increase Protein Synthesis in Articular Cartilage Explants. J Orthop Res 12: 151-60, 1994.
  10. Shimizu, T., et al. Bone ingrowth into porous calcium phosphate ceramics; influence of pulsating electromagnetic field. J Orthop Res 6: 248-258, 1988.
  11. Rubin, C, McLeod, K and Lanyon, L. Prevention of osteoporosis by pulsed electromagnetic fields. J Bone Joint Surg [Am] 71: 411-416, 1989.
  12. Cruess, R. and Bassett, CAL. The effect of pulsing electromagnetic fields on bone metabolism in experimental disuse osteoporosis. Clin Orthop 173: 345-250, 1983.
  13. Miller, G., et al. Electromagnetic stimulation of canine bone grafts. J Bone and Joint Surg [Am} 66: 693-698, 1984.
  14. Kold, S. and Hickman, J. Preliminary study of quantitative aspects and the effect of pulsed electromagnetic field treatment on the incorporation of equine cancellous bone rafts. Eq Vet J 19(2): 120-124, 1987.
  15. Sharrard, W. A double blind trial of pulsed electromagnetic fiedls for delayed union of tibial fractures. J Bone and Joint Surg [Br] 72: 347-355, 1990.
  16. Mooney, V. A randomized double blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions. Spine 15: 708-712, 1990.
  17. De Haas, W.G., Lazarovici, M.A., and Morrison, D.M. The Effect of Low Frequency Magnetic Field on Healing of Osteotomized Rabbit Radius. Clin Orthop 145: 245-51, 1979.
  18. Ieran, M., et al. Effect of Low Frequency Pulsing Electromagnetic Fiedls on Skin Ulcers of Venous Origin in Humans: A Double-Blind Study. J Orthop Res 8(2): 276-282, 1990.
  19. Kort, J., Ito, H. and Basset, C.A.L. Effects of pulsing electromagnetic fields on peripheral nerve regeneration. J Bone Jt Sug Orthop Trans 4: 238, 1980.
  20. Sisken, B.F., et al. Pulsed electromagnetic fiedls stimulate nerve regeneration in vitro and in vivo. Restorative Neurology and Neuroscience 1: 303-309, 1990b.
  21. Polk, C. Electric and Magnetic Fields for Bone and Soft Tissue Repair. In, Handbook of Biological Effects of Electromagnetic Fields, 2nd ed. Polk, C. and Postow, E., eds. CRC Press, Boca Raton, FL, 231-246, 1996.
  22. Bassett, C.A.L. Beneficial Effects of Electromagnetic Fields. J of Cell Biochem 51: 387-393, 1993.
  23. Lee, E.W., et al. Pulsed Magnetic and Electromagnetic Fields in Experimental Achilles Tendonitis in the Rat: A Prospective Randomized Study. Arch Phys Med and Rehab 78(4): 399-404, 1997.
  24. Barker, A.T. Pulsating Electromagnetic Field Therapy for the Treatment of Tibial Non-Union Fractures. Lancet 8384 (1): 994-996, 1984.
  25. Barker, A.T. Electricity, magnetism and the body: Some Uses and Abuses. Eng Sci and Edu J, 249-256, December, 1993.
  26. Aaron, R. Department of Orthopedics, Brown University and Orthopedic Research Laboratory, Department of Surgery, Roger Williams Medical Center, Providence, RI. Personal Communication.
  27. Schulten, K. Magnetic field effects in chemistry and biology. Adv. Solid State Phys. 22: 61, 1982.
  28. Steiner, U.E. and Ulrich, T. Magnetic field effects in chemical kinetics and related phenomena. Chem Rev, 89: 51, 1989.
  29. Beall, P.T., Hazlewood, C.F. and Rao, P.N. Nuclear magnetic resonance patterns of intracellular water as a function of HeLa cell cycle. Science 192: 904-907, 1976.
  30. Frankel, R.B. and Liburdy, R.P. Biological Effects of Static Magnetic Fields. In, Polk, C. and Postow, E. Handbook of Biological Effects of Electromagnetic Fields, 2nd Ed. CRC Press, Boca Raton, FL, 149-183, 1996.
  31. Porter, M. Magnetic Therapy. Equine Vet Data, 17(7): 371, 1997.
  32. Kirschvink, J. Professor of Geobiology, California Institute of Technology, Pasadena, CA. Personal Communication, 1997.
  33. Baermann, H. Bioflex, Flexible Concentric Circle Magnets vs. Elekiban Style Magnets. www.magnaflex.com
  34. Adair, R.K. Sterling Professor Emeritus of Physics, Yale University, New Haven, CT. Personal Communication.
  35. Tectonic Magnets, Riviera Beach, FL.
  36. Pratt, G. Professor of Electrical Engineering, The Massachusetts Institute of Technology, Cambridge, MA. Personal Communication, 1997.
  37. Kobluk, C., Johnston, G. and Lauper, L. A Scintigraphic Investigation of Magnetic Field Therapy on the Equine Third Metacarpus. Vet and Comp Orthop and Traum 7(1): 9-13, 1994.
  38. Steyn, P. Professor of Radiology, Department of Veterinary Medicine, Colorado State University, Personal Communication, 1997.
  39. Saygili, G., et al. Investigation of the Effect of Magnetic Retention Systems Used in Prosthodontics on Buccal Mucosal Blood Flow. Int J of Prosthodont, 5(4): 326-332, 1992.
  40. Belossi, A., et al. No Effect of a Low-Frequency Pulsed Magnetic Field on the Brain Blood Flow Among Mice. Panminerva Med, 35(1): 57-59, 1993.
  41. Barker, A. and Cain, M. The claimed vasodilatory effect of a commercial permanent magnet foil; results of a double blind trial. Clin Phys Physiol Meas 6(3): 261-263, 1985.
  42. Leaper, D.J. Do Magnetic Fields Influence Soft Tissue Wound Healing? Eq Vet J 17(3): 178-180, 1985.
  43. Turner, T., Wolfsdorf, K. and Jourdenais, J. Effects of Heat, Cold, Biomagnets and Ultrasound on Skin Circulation in the Horse. Proc 37th AAEP, 249-257, 1991.
  44. Stick, C., et al. Do Strong Magnetic Fields in NMR tomography modify tissue perfusion? Nuklearmedizin 154: 326, 1991
  45. Keltner, J., et al. Magnetohydrodynamics of Blood Flow. Mag Res in Med 16: 139, 1990.
  46. Wikswo, J.P. and Barach, J.P. An estimate of the Steady Magnetic Field Strength required to influence nerve conduction. IEEE Transactions on Biomedical Engineering BME-27(12): 722-723, 1980.
  47. Trock, D.H., Bollet, A.J. and Markill, R. The effect of pulsed electromagnetic fields in the treatment of osteoarthritis of the knee and cervical spine. Report of randomized, double blind, placebo controlled trials. J Rheumatol 21(10): 1903-1911, 1994.
  48. Trock, D.H., et al. A double-blind trial of the clinical effects of pulsed electromagnetic fields in osteoarthritis. J Rheumatol 20(3): 456-460, 1993.
  49. Foley-Nolan, D., et al. Pulsed High Frequency (27MHz) Electromagnetic Therapy for Persistent Neck Pain: A Double Blind, Placebo-Controlled Study of 20 Patients. Orthopedics 13(4): 445-451, 1990.
  50. Varcaccia-Garofalo, G., et al. Analgesic properties of electromagnetic field therapy in patients with chronic pelvic pain. Clin Exp Obstet Gynecol 22(4): 350-354, 1995.
  51. Leclaire, R and Bourgouin, J. Electromagnetic treatment of shoulder periarthritis: a randomized controlled trial of the efficiency and tolerance of magnetotherapy. Arch Phys Med Rehabil 72(5): 284-287, 1991.
  52. Puett, D.W. and Griffin, M.R. Published trials of nonmedicinal and noninvasive therapies for hip and knee osteoarthritis. Ann Intern Med 121(2): 133-140, 1994.
  53. Papi, F., et al. Exposure to Oscillating Magnetic Fields Influences Sensitivity to Electrical Stimuli. II. Experiments on Humans. Bioelectromagnetics 16: 295-300, 1995.
  54. Nakagawa, K. Clinical Application of Magnetic Field. J Soc Non-trad. Technol., 66: 6-17, 1974.
  55. Nakagawa, K. Magnetic field-deficient syndrome and magnetic treatment. Jap Med J 2745: 24-32, 1976.
  56. Vallbonna, C., Hazlewood, C.F. and Jurida, G. Response of Pain to Static Magnetic Fields in Postpolio Patients: A Double-Blind Pilot Study. Arch Phys Med Rehabil 78: 1200-1204, 1997.
  57. Casselli, M.A., et al. Evaluation of magnetic foil and PPT Insoles in the treatment of heel pain. J Am Podiatr Med Assoc 87(1): 11-16, 1997.
  58. Hong, C., et al. Magnetic necklace: its therapeutic effectiveness on neck and shoulder pain. Arch Phys Med Reab. 63: 464-466, 1982.
  59. Lin, J.C., et al. Geophysical Variables and Behavior: XXVII. Magnetic Necklace: Its Therapeutic Effectiveness on Neck and Shoulder Pain: 2. Psychological Assessment. Psychological Reports 56: 639-649, 1985.
  60. Watkins, J., et al: Healing of surgically created defects in the Equine Superficial Digital Flexor Tendon: Effects of PEMF on collagen-type transformation and tissue morphologic reorganization. AJVR 46: 2097-2103, 1985.
  61. Bramlage, L., Weisbrode, S. and Spurlock, G. The Effect of a Pulsating Electromagnetic Field on the Acute Healing of Equine Cortical Bone. Proc 30th AAEP, 43-48, 1984.
  62. Cane, V., Botti, P. and Soana, S. Pulsed Magnetic Fields Improve Osteoblast Activity During the Repair of an Experiemental Osseous Defect. J Ortho Research, 11(5): 664-670, 1993.
  63. Collier, M., et al. Radioisotope uptake in normal equine bone under the influence of a pulsed electromagnetic field. Mod Vet Prac 66: 971-974, 1985.
  64. Turpin, R. Characterization of Quack Theories. http://www.chewable.com/hypatian/quack.htm.
  65. Walker, R.D. Antimicrobial Chemotherapy. In, Current Therapy in Equine Medicine, III, Robinson, N.E., ed. W.B. Saunders Co, Philadelphia, PA, 1992.

 

Simply, quick ways of deciding quack issues without looking at the evidence.[i] 

1.  There is no reasonable modus operandi. 

 

2.  Failure to find widespread application by physicians. 

 

3.  Failure to be published in a major peer-review medical journal. 

 

4.  Reliance upon testimonials, including by scientists and physicians.  .

 

5.  The results are contrary to a large body of experimental, published results.

 

1.  Reasonable entails a method of operation that is supported by known and documented biological pathways.  There is no known mechanism in the cells of the body designed to be influenced by a magnet—that strong magnetism might well over prolonged periods of time prove disruptive of biochemical reactions.  (People are routinely subjected to a strong field for nearly an hour when having an MRI).  Since magnets are not used to influence in the laboratory chemical reactions, a reasonable conclusion is that they don’t in the body as well.  Secondly the effects are much more likely to be disruptive rather than therapeutic.  For vitamin C, for example, has special receptors in the body, but for magnetic fields there aren’t. 

 

2.  This is very telling for other the centuries there are tens of thousands of purported treatments that either fail to be demonstrated as effective or have vanish.  Most medical treatments have a body of published results supporting their use, and thus in most instance gain wide-spread acceptance.  Controversies are generally over which alternative is best.

 

3.  Any treatment worth its salt will be tested and the results submitted to a medical journal.  If magnet on the wrist cured liver dysfunction, then the manufacturer of that product ought to advance its marketing by having a study done and then published in an important medical journal.  Being published does not prove the case:  there are trade publications for alternative treatments and their review of the submitted work is scanty at best. 

 

4.  True believers are as much a proof of angels dancing on the head of pins as that of the curative property of the magnet.  And just as there are scientists who profess to believe in a young world, so to are there physicians and researchers whose beliefs are equally questionable.  These are the exceptions and they don’t prove the case. 

 

5.  Reproducibility is part of the gold standard.  A result that stands in conflict to a large body of evidence is always more like to be in error. 

 

Consider the following example (from http://quackwatch.org/04ConsumerEducation/QA/magnet.html)by Stephen Barrett, MD. 

The main basis for the claims is a double-blind test study, conducted at Baylor College of Medicine in Houston, which compared the effects of magnets and sham magnets on knee pain. The study involved 50 adult patients with pain related to having been infected with the polio virus when they were children. A static magnetic device or a placebo device was applied to the patient's skin for 45 minutes. The patients were asked to rate how much pain they experienced when a "trigger point was touched." The researchers reported that the 29 patients exposed to the magnetic device achieved lower pain scores than did the 21 who were exposed to the placebo device [3} Although this study is cited by nearly everyone selling magnets, it provides no legitimate basis for concluding that magnets offer any health-related benefit:

  • Although the groups were said to be selected randomly, the ratio of women to men in the experimental group was twice that of the control group. If women happen to be more responsive to placebos than men, a surplus of women in the "treatment" group would tend to improve that group's score.
  • The age of the placebo group was four years higher than that of the control group. If advanced age makes a person more difficult to treat, the "treatment" group would again have a scoring advantage.
  • The investigators did not measure the exact pressure exerted by the blunt object at the trigger point before and after the study.
  • Even if the above considerations have no significance, the study should not be extrapolated to suggest that other types of pain can be relieved by magnets.
  • There was just one brief exposure and no systematic follow-up of patients. Thus there was no way to tell whether any improvement would be more than temporary.
  • The authors themselves acknowledge that the study was a "pilot study." Pilot studies are done to determine whether it makes sense to invest in a larger more definitive study. They never provide a legitimate basis for marketing any product as effective against any symptom or health problem.

Two better-designed, longer-lasting pain studies have been negative:

  • Researchers at the New York College of Podiatric Medicine have reported negative results in a study of patients with heel pain. Over a 4-week period, 19 patients wore a molded insole containing a magnetic foil, while 15 patients wore the same type of insole with no magnetic foil. In both groups, 60% reported improvement, which suggests that the magnetic foil conveyed no benefit [4].
  • More recently, researchers at the VA Medical Center in Prescott, Arizona conducted a randomized, double-blind, placebo-controlled, crossover study involving 20 patients with chronic back pain. Each patient was exposed to real and sham bipolar permanent magnets during alternate weeks, for 6 hours per day, 3 days per week for a week, with a 1-week period between the treatment weeks. No difference in pain or mobility was found between the treatment and sham-treatment periods [5].

 



[i]   This presumes a basic understanding of our body, such as one would obtain from a suburban high school health class coupled with a biology class.

 

Enter supporting content here